1 00:00:02,280 --> 00:00:05,120 It's Britain's favourite class A drug. 2 00:00:05,120 --> 00:00:08,640 There's loads of nicknames for it, chang, bugle. 3 00:00:08,640 --> 00:00:11,680 Sniff, coke or snow. Chop, charge. 4 00:00:11,680 --> 00:00:13,600 Flake, blow. 5 00:00:13,600 --> 00:00:16,880 Cocaine, once a drug exclusively for the rich and famous, 6 00:00:16,880 --> 00:00:19,200 has never been more popular. 7 00:00:19,200 --> 00:00:22,360 I'm feelin' buzzin', mate. Buzzin'! 8 00:00:22,360 --> 00:00:28,720 In 2009, it was taken by around 1.2 million people in the UK alone. 9 00:00:28,720 --> 00:00:31,160 This is nice, proper - boom! 10 00:00:31,160 --> 00:00:35,440 But for some people, a few lines of coke became a life-changing event. 11 00:00:35,440 --> 00:00:38,880 No matter how long I chased that first high I never got close to it, 12 00:00:38,880 --> 00:00:40,000 never again. 13 00:00:40,000 --> 00:00:43,120 This is the inside story of how cocaine works. 14 00:00:43,120 --> 00:00:46,200 There's euphoria, confidence, talkativeness. 15 00:00:46,200 --> 00:00:48,560 Oh, go on, rack us one up, then. 16 00:00:48,560 --> 00:00:49,760 Go on, then. 17 00:00:49,760 --> 00:00:52,240 We follow three users on nights out on coke 18 00:00:52,240 --> 00:00:55,280 and journey inside their bodies and brains 19 00:00:55,280 --> 00:00:59,160 to find out how the drug creates its highs... 20 00:01:01,400 --> 00:01:02,800 ..and lows. 21 00:01:04,840 --> 00:01:08,040 We'll access Britain's leading experts to find out the truth 22 00:01:08,040 --> 00:01:10,800 behind cocaine's controversial reputation. 23 00:01:10,800 --> 00:01:13,360 In the first hour after taking cocaine, 24 00:01:13,360 --> 00:01:17,400 the risk of having a heart attack increases by twenty-fold. 25 00:01:17,400 --> 00:01:21,600 I have seen patients where the whole middle of the nose has gone, effectively, 26 00:01:21,600 --> 00:01:23,320 and you just have one nasal cavity 27 00:01:23,320 --> 00:01:25,440 and everything just collapses inwards. 28 00:01:25,440 --> 00:01:28,920 We'll find out how cocaine has changed some people permanently... 29 00:01:28,920 --> 00:01:31,960 I didn't realise the effect it would have on people 30 00:01:31,960 --> 00:01:34,920 until you are there in... Well, you could say a death bed. 31 00:01:34,920 --> 00:01:37,840 ..and investigate just how widespread 32 00:01:37,840 --> 00:01:39,680 the drug has really become. 33 00:01:39,680 --> 00:01:41,760 It literally is everywhere. 34 00:01:41,760 --> 00:01:45,880 Cocaine - the perfect pick-me-up or a class A killer? 35 00:02:00,680 --> 00:02:05,440 Possession of even a small amount of cocaine can get you seven years in prison. 36 00:02:05,440 --> 00:02:11,240 Despite this, more than 120 tonnes were snorted in Britain in 2009 37 00:02:11,240 --> 00:02:13,920 enough to make 2.4 billion lines, 38 00:02:13,920 --> 00:02:17,280 stretching nearly three times round the world. 39 00:02:17,280 --> 00:02:21,760 Cocaine is most popular amongst 16 to 29-years-olds, 40 00:02:21,760 --> 00:02:24,960 with one in 20 estimated to have taken it last year. 41 00:02:25,960 --> 00:02:29,600 Josie and Damian have both been occasional cocaine users 42 00:02:29,600 --> 00:02:31,200 since they were teenagers. 43 00:02:31,200 --> 00:02:34,560 They became friends after meeting at a house party in Bristol, 44 00:02:34,560 --> 00:02:35,720 where they both live. 45 00:02:35,720 --> 00:02:37,880 Damian is a 29-year-old entrepreneur. 46 00:02:37,880 --> 00:02:43,840 Im interested in horticulture, tropical palm trees, hoping to import 47 00:02:43,840 --> 00:02:47,800 some from countries where they are cheap and we can distribute them 48 00:02:47,800 --> 00:02:49,880 in England and make maximum profit. 49 00:02:49,880 --> 00:02:52,040 (INAUDIBLE) ..in a couple of weeks. 50 00:02:52,040 --> 00:02:56,080 I'm doing a fire show there, but I've got to do it before I get too drunk. 51 00:02:56,080 --> 00:02:59,400 Josie is 21 and works at music festivals in the summer. 52 00:02:59,400 --> 00:03:02,000 I don't take coke that often I don't really, like, 53 00:03:02,000 --> 00:03:05,120 spend lots of money on it, but if it's there I'll do it, like. 54 00:03:07,600 --> 00:03:09,920 Josie is having a house party tonight 55 00:03:09,920 --> 00:03:13,720 and Damian is planning to get some cocaine in for the event. 56 00:03:15,240 --> 00:03:18,000 They both take it a couple of times a month on average. 57 00:03:18,000 --> 00:03:20,240 Right. We need to sort this party out. 58 00:03:20,240 --> 00:03:23,560 Top of the agenda is to order the coke in. 59 00:03:23,560 --> 00:03:27,080 First time I took coke I literally just took it, smoked a cigarette, 60 00:03:27,080 --> 00:03:31,600 puked everywhere, then straight after I puked I just felt bloody amazing, 61 00:03:31,600 --> 00:03:33,680 just like absolutely amazing. 62 00:03:33,680 --> 00:03:37,840 It just felt like all my worries had been lifted up from my shoulders, 63 00:03:37,840 --> 00:03:39,680 er, just felt really confident. 64 00:03:39,680 --> 00:03:45,920 Drink of cider, little line, gets you ready for the night, innit? 65 00:03:45,920 --> 00:03:50,480 With the supplies arranged, Josie sets about decorating the house. 66 00:03:50,480 --> 00:03:53,400 She's also organised a sound system. 67 00:03:53,400 --> 00:03:57,200 Come on, boys, let's get these speakers inside! 68 00:03:58,800 --> 00:04:00,600 CAR BEEPS HORN 69 00:04:01,040 --> 00:04:05,640 For Damian, cocaine is a drug best taken amongst friends at home. 70 00:04:05,640 --> 00:04:08,000 I enjoy it more when I come back from a club when 71 00:04:08,000 --> 00:04:09,160 I'm feeling a bit like 72 00:04:09,160 --> 00:04:11,320 worse for wear and then get it up your nose 73 00:04:11,320 --> 00:04:13,440 and then you've got a good house party. 74 00:04:13,440 --> 00:04:15,600 I think coke's quite a private thing, anyway. 75 00:04:15,600 --> 00:04:18,120 I prefer it to be at home. 76 00:04:18,120 --> 00:04:22,120 House decorated and sound system built, Josie and Damian 77 00:04:22,120 --> 00:04:24,760 start their Saturday night as they mean to go on. 78 00:04:24,760 --> 00:04:26,920 You just chop it up, 79 00:04:26,920 --> 00:04:29,680 with a card, you get your snorty-worty. 80 00:04:34,480 --> 00:04:40,520 As Damian snorts his line, it flies up into his nose at up to 100 mph. 81 00:04:40,520 --> 00:04:42,800 The fine powder rips through his nostrils, 82 00:04:42,800 --> 00:04:46,440 coating the mucous membranes lining his sinuses. 83 00:04:46,440 --> 00:04:50,240 Up to 60% of the powder gets absorbed through the nasal membranes 84 00:04:50,240 --> 00:04:53,120 straight into his bloodstream via small capillaries, 85 00:04:53,120 --> 00:04:56,320 beginning a journey through his body. 86 00:04:56,320 --> 00:04:58,680 These capillaries feed into bigger veins 87 00:04:58,680 --> 00:05:01,480 leading eventually to Damian's heart. 88 00:05:04,040 --> 00:05:07,120 The cocaine is then pumped on to his lungs, 89 00:05:07,120 --> 00:05:09,520 where the blood absorbs oxygen... 90 00:05:11,320 --> 00:05:13,560 ..before shooting back up to his heart, 91 00:05:13,560 --> 00:05:18,600 which is starting to beat faster as the cocaine takes effect. 92 00:05:18,600 --> 00:05:23,240 The cocaine payload is carried on to the major organs in his body. 93 00:05:23,240 --> 00:05:25,720 Much of it to Damian's brain. 94 00:05:27,680 --> 00:05:31,840 Here the cocaine molecules can leech up through the blood vessels. 95 00:05:31,840 --> 00:05:34,240 Soon they reach the billions of nerve cells 96 00:05:34,240 --> 00:05:36,040 that Damian's brain is made of - 97 00:05:36,040 --> 00:05:39,520 the cells that control every aspect of how he behaves. 98 00:05:41,720 --> 00:05:44,000 Beautiful. All right! 99 00:05:44,000 --> 00:05:45,840 It was pretty ... awesome. 100 00:05:45,840 --> 00:05:47,240 Yeah. Good, good. 101 00:05:49,600 --> 00:05:52,440 A United Nations report estimated 16 million people 102 00:05:52,440 --> 00:05:55,640 round the world took coke in 2008 alone. 103 00:05:55,640 --> 00:05:59,160 This global appetite has created an industry 104 00:05:59,160 --> 00:06:02,400 with a turnover of around £55 billion a year - 105 00:06:02,400 --> 00:06:05,840 more than Google, McDonalds and Coca Cola put together. 106 00:06:07,000 --> 00:06:12,440 Cocaine is produced from the leaves of the coca plant in South America. 107 00:06:14,920 --> 00:06:18,400 In makeshift laboratories, deep in the heart of the rainforest, 108 00:06:18,400 --> 00:06:22,120 coca leaves are transformed from a naturally occurring mild stimulant 109 00:06:22,120 --> 00:06:26,280 to a powerful drug capable of changing the way we think and feel. 110 00:06:26,280 --> 00:06:30,280 The production uses an array of potent and often poisonous substances 111 00:06:30,280 --> 00:06:34,040 including sulphuric acid and kerosene. 112 00:06:34,040 --> 00:06:36,200 The result, a pure white crystal, 113 00:06:36,200 --> 00:06:38,560 is worth just a £100 a kilo where it is made, 114 00:06:38,560 --> 00:06:43,720 but £50,000 a kilo by the time it reaches the UK. 115 00:06:44,720 --> 00:06:49,240 Between 2008 and 2009, the number of people taking cocaine regularly 116 00:06:49,240 --> 00:06:51,360 in the UK rose by around 200,000. 117 00:06:51,360 --> 00:06:55,640 As supplies have grown to satisfy the increasing demand, 118 00:06:55,640 --> 00:06:56,960 prices have plummeted. 119 00:06:56,960 --> 00:07:00,400 A line can now cost as little as £2, 120 00:07:00,400 --> 00:07:04,480 and the low price has made cocaine more accessible than ever. 121 00:07:09,280 --> 00:07:13,400 Liam has just left the army and moved back to his home town 122 00:07:13,400 --> 00:07:15,680 to be close to his family and friends. 123 00:07:15,680 --> 00:07:18,400 'When I'm with my mates, we like to go the local pubs, 124 00:07:18,400 --> 00:07:19,600 'we go down town a lot,' 125 00:07:19,600 --> 00:07:24,080 we have a laugh, we socialise a lot. Round here, everyone knows everyone. 126 00:07:24,080 --> 00:07:27,440 He's looking for a new career in the construction industry. 127 00:07:30,600 --> 00:07:33,720 In an effort to limit the documentary's impact on his future, 128 00:07:33,720 --> 00:07:36,000 he's decided not to use his real name. 129 00:07:36,000 --> 00:07:39,240 It's good when you're having a drink and socialising, I think. 130 00:07:39,240 --> 00:07:43,000 You have a few, like a little cheeky one, a little perker and, you know, 131 00:07:43,000 --> 00:07:44,640 puts you in the mood, man. 132 00:07:44,640 --> 00:07:47,000 Last time we were sniffing lines like that. 133 00:07:47,000 --> 00:07:48,800 Madness, swear to God. 134 00:07:48,800 --> 00:07:52,360 The first time you feel it, nothing'll compare to that. 135 00:07:52,360 --> 00:07:54,280 Although money is tight, 136 00:07:54,280 --> 00:07:57,480 Liam enjoys a coke session every couple of months. 137 00:07:57,480 --> 00:08:01,360 'When you're racking up and you're like, you, you do your line,' 138 00:08:01,360 --> 00:08:03,880 you're buzzing a bit, you get a little buzz. 139 00:08:03,880 --> 00:08:04,920 Yeah! 140 00:08:04,920 --> 00:08:08,640 You get a buzz racking it up and then you're buzzing when you're at it. 141 00:08:11,560 --> 00:08:13,760 Liam's got some cocaine in today, 142 00:08:13,760 --> 00:08:17,040 but he doesn't want to wait until the evening to get started. 143 00:08:21,080 --> 00:08:24,600 The effect of the cocaine is dramatic. 144 00:08:28,960 --> 00:08:31,200 This is nice, proper - boom! 145 00:08:31,200 --> 00:08:33,520 It was tasty and all. 146 00:08:33,520 --> 00:08:37,280 THEY SHOUT AND LAUGH 147 00:08:37,280 --> 00:08:41,000 'If you have a fat line, it's a rush, man. Say you have 148 00:08:41,000 --> 00:08:43,680 'an energy drink and you feel a bit better,' 149 00:08:43,680 --> 00:08:45,120 that's like 50 times that. 150 00:08:45,120 --> 00:08:48,040 It's like - whoosh! It's straight in your bloodstream. 151 00:08:48,040 --> 00:08:49,480 And you feel the... 152 00:08:49,480 --> 00:08:53,360 Ryan's sudden high and burst of energy come from 153 00:08:53,360 --> 00:08:56,280 the huge changes that have just happened in his brain. 154 00:09:01,000 --> 00:09:05,480 Our brains are composed of networks of billions of tiny nerve cells. 155 00:09:07,920 --> 00:09:10,160 Signals race around these networks, 156 00:09:10,160 --> 00:09:14,440 crossing the gaps between the nerve cells using chemical messengers. 157 00:09:15,720 --> 00:09:18,360 One network is dedicated to making us feel good 158 00:09:18,360 --> 00:09:21,200 when we do something that is essential to survival 159 00:09:21,200 --> 00:09:23,920 such as eat, drink or have sex. 160 00:09:25,320 --> 00:09:28,320 Normally, when this network is activated, 161 00:09:28,320 --> 00:09:29,520 the nerve cells in it 162 00:09:29,520 --> 00:09:32,920 release the feel-good chemical messenger dopamine. 163 00:09:32,920 --> 00:09:35,640 Dopamine travels across the gap from one nerve cell 164 00:09:35,640 --> 00:09:37,320 to receptors on its neighbour, 165 00:09:37,320 --> 00:09:41,000 triggering a chain reaction which makes you feel good. 166 00:09:41,000 --> 00:09:44,520 This dopamine then returns to the nerve cell that released it 167 00:09:44,520 --> 00:09:46,160 for further use. 168 00:09:48,880 --> 00:09:52,840 Cocaine hijacks the feel-good network in the brain. 169 00:09:52,840 --> 00:09:55,960 It causes huge increases in the amount of dopamine 170 00:09:55,960 --> 00:09:57,480 throughout the network, 171 00:09:57,480 --> 00:10:00,280 flooding the brain with feel-good chemicals. 172 00:10:00,280 --> 00:10:03,880 And it also stops the dopamine returning to the nerve cells 173 00:10:03,880 --> 00:10:05,280 that have released it, 174 00:10:05,280 --> 00:10:07,760 meaning more and more builds up. 175 00:10:07,760 --> 00:10:11,400 Cocaine blocks something called the dopamine transporter, 176 00:10:11,400 --> 00:10:13,680 and what that does is it mops up dopamine 177 00:10:13,680 --> 00:10:16,200 that sits in the space in between two cells. 178 00:10:16,200 --> 00:10:19,240 And if that re-uptake is blocked, 179 00:10:19,240 --> 00:10:22,960 what you get is an awful lot of dopamine floating around this space. 180 00:10:25,560 --> 00:10:28,320 The flood of dopamine sends the feel-good network 181 00:10:28,320 --> 00:10:30,120 in the brain into overdrive, 182 00:10:30,120 --> 00:10:32,760 producing a sense of euphoria and self-assurance 183 00:10:32,760 --> 00:10:35,560 making the user more animated and talkative. 184 00:10:35,560 --> 00:10:37,960 Hey hey! No way! 185 00:10:37,960 --> 00:10:42,800 Since filming, we've had to conceal the identity of Liam's friend 186 00:10:42,800 --> 00:10:44,800 for legal reasons. 187 00:10:44,800 --> 00:10:48,320 Its not like energy. That's what amphetamine is. That's energy. 188 00:10:48,320 --> 00:10:51,440 Cocaine's more of a, like... 189 00:10:51,440 --> 00:10:53,880 A clean, I swear. It makes you feel fresher. 190 00:10:53,880 --> 00:10:57,320 Its all about how you're feeling on the day. 191 00:10:57,320 --> 00:10:58,400 And who you're with. 192 00:11:02,040 --> 00:11:04,200 Cocaine's main effects are emotional. 193 00:11:04,200 --> 00:11:10,080 The user quite rapidly feels more confident, talkative, assertive, 194 00:11:10,080 --> 00:11:13,880 sometimes quite garrulous, even aggressive, 195 00:11:13,880 --> 00:11:18,240 and all of those effects relate to the amount of cocaine that's taken. 196 00:11:22,160 --> 00:11:26,560 Back in Bristol, Damian and Josie are getting in a second line 197 00:11:26,560 --> 00:11:29,040 before the guests start to arrive. 198 00:11:32,560 --> 00:11:35,840 The second one. You've got to have one after another, 199 00:11:35,840 --> 00:11:39,320 especially the first one, just to get you super-high, innit, Jos? 200 00:11:41,920 --> 00:11:45,880 Oh, go on, rack us up one, then. Go on, then. 201 00:11:45,880 --> 00:11:49,400 What am I supposed to do? Stand here and watch him snorting it? 202 00:11:50,560 --> 00:11:52,640 I think we can make it bigger than that. 203 00:11:52,640 --> 00:11:55,240 Come on, Jos. 204 00:11:55,520 --> 00:11:57,760 Get that down you, Josie. 205 00:12:01,360 --> 00:12:03,160 All right! 206 00:12:09,840 --> 00:12:12,520 'You feel like you gotta do stuff, you gotta do something, 207 00:12:12,520 --> 00:12:16,280 'you gotta run around, climb the walls, like, dance,' 208 00:12:16,280 --> 00:12:20,320 you gotta, you know, go on a rampage. 209 00:12:24,000 --> 00:12:26,120 Transform...! 210 00:12:26,120 --> 00:12:28,240 Pow, pow! 211 00:12:28,240 --> 00:12:30,560 Bagpuss in the house. 212 00:12:30,560 --> 00:12:33,040 I'm feeling buzzing', mate. Buzzin'! 213 00:12:34,640 --> 00:12:40,280 Innit, Alfina? She knows. I mean, look at the size of her nose. 214 00:12:44,000 --> 00:12:48,400 'Definitely cocaine makes you want to dance.' 215 00:12:48,400 --> 00:12:50,480 Makes you feel horny as well so, erm, 216 00:12:50,480 --> 00:12:54,240 you, er, generally want to dance next to really good-looking girls. 217 00:12:57,080 --> 00:13:00,720 Feelings of excitement and sexual desire are caused by the release of 218 00:13:00,720 --> 00:13:04,800 dopamine and noradrenaline, another chemical messenger in the brain. 219 00:13:04,800 --> 00:13:09,880 It floods into the feel-good network and also the emotional centre. 220 00:13:09,880 --> 00:13:13,160 Noradrenaline is normally released when you're in danger. 221 00:13:13,160 --> 00:13:15,760 It makes you more alert and ready for action. 222 00:13:17,320 --> 00:13:19,920 Cocaine also suppresses the area of the brain 223 00:13:19,920 --> 00:13:24,800 involved in decision-making. This makes people more impulsive. 224 00:13:24,800 --> 00:13:27,200 LIAM: It does definitely make you feel horny. 225 00:13:27,200 --> 00:13:28,640 It's a horny drug. 226 00:13:28,640 --> 00:13:31,720 Say you're having sex with a bird, man, if she's on it as well, 227 00:13:31,720 --> 00:13:34,080 I'm going to have a good night then. 228 00:13:34,080 --> 00:13:37,680 It does help, man, I swear. It's like a Viagra-type thing. 229 00:13:37,680 --> 00:13:40,040 Coke definitely changes your sex drive, 230 00:13:40,040 --> 00:13:41,920 you just want to have sex all night. 231 00:13:41,920 --> 00:13:43,840 Or all day, whenever you take coke. 232 00:13:43,840 --> 00:13:47,320 'Er, I would say sex is better on coke, yeah. Yeah, definitely. 233 00:13:47,320 --> 00:13:52,160 'As much as it numbs you, er,' 234 00:13:52,160 --> 00:13:58,600 it accentuates everything so you can do a lot of things for longer, 235 00:13:58,600 --> 00:14:01,560 erm, which is a good thing. 236 00:14:01,560 --> 00:14:07,360 This is because cocaine makes the body produce a chemical which increases blood flow to the penis. 237 00:14:07,360 --> 00:14:13,000 stimulating an erection, just like Viagra. The chemical also delays ejaculation. 238 00:14:14,360 --> 00:14:19,480 But it can cause problems - if users take cocaine regularly, or take a lot 239 00:14:19,480 --> 00:14:26,560 in one session, it can produce too much noradrenaline in an area of the brain called the hippocampus. 240 00:14:26,560 --> 00:14:30,760 This can stop male users getting an erection. 241 00:14:30,760 --> 00:14:35,920 Sometimes you can't get a hard-on if you've had too much, like. Nothing there. 242 00:14:38,280 --> 00:14:42,120 People have always been drawn to the stimulating powers of the coca plant. 243 00:14:42,120 --> 00:14:47,000 Indigenous tribes have been chewing the unrefined leaves for at least eight thousand years. 244 00:14:48,760 --> 00:14:52,840 But it wasn't until 1860 that a German chemist finally cracked 245 00:14:52,840 --> 00:14:57,320 how to get the active ingredient from the leaves, and cocaine was born. 246 00:15:01,280 --> 00:15:05,760 Soon it was discovered that cocaine was an anaesthetic, 247 00:15:05,760 --> 00:15:08,640 the first ever found, and it revolutionised medicine. 248 00:15:08,640 --> 00:15:11,920 I have the grandest headache medicine in the world - try it. 249 00:15:18,000 --> 00:15:20,960 There was an explosion in legal highs. You could find cocaine 250 00:15:20,960 --> 00:15:24,040 in everything from tooth drops to haemorrhoid plasters. 251 00:15:24,040 --> 00:15:29,440 It's reported even Coca Cola used to pack 60mg of cocaine into every serving. 252 00:15:29,440 --> 00:15:34,720 But by the turn of the 20th century, cocaine was becoming too popular. 253 00:15:34,720 --> 00:15:39,280 The dangers of addiction were realised and it was outlawed round the world. 254 00:15:39,280 --> 00:15:40,800 It looked like cocaine was set to become a part of history. 255 00:15:40,800 --> 00:15:45,280 But it didn't work out how the lawmakers hoped. 256 00:15:51,800 --> 00:15:56,800 Today, cocaine is more widespread than ever and presents a massive problem for the police. 257 00:15:59,760 --> 00:16:04,920 Five thousand people are sentenced for possessing or selling cocaine every year in the UK. 258 00:16:04,920 --> 00:16:08,920 But it is estimated that the police only seize about 1.3 per cent 259 00:16:08,920 --> 00:16:11,120 of the cocaine distributed in Britain. 260 00:16:11,120 --> 00:16:14,000 Stay still. 261 00:16:20,120 --> 00:16:26,080 PC Adrian Parsons, the Drugs Liaison Officer for Kent Police, is fighting back. 262 00:16:29,480 --> 00:16:33,400 He uses cutting-edge technology to prove that drug dealers' money 263 00:16:33,400 --> 00:16:37,000 has come from selling cocaine so that it can be confiscated from them. 264 00:16:37,000 --> 00:16:41,200 This is an ion track itemiser. It's a drug detection machine. 265 00:16:41,200 --> 00:16:44,280 It's looking for traces of drugs rather than bulk amounts. 266 00:16:44,280 --> 00:16:46,960 It's looking for stuff that you can't see. 267 00:16:46,960 --> 00:16:52,440 The whole banking system has been contaminated with cocaine from drug dealers' and users' money. 268 00:16:52,440 --> 00:16:56,880 Using the most sophisticated system to do this, if you took ten notes off the street, 269 00:16:56,880 --> 00:17:00,440 the likelihood is that at least nine of them will be contaminated with cocaine. 270 00:17:00,440 --> 00:17:03,240 It contaminates everything, it literally is everywhere. 271 00:17:03,240 --> 00:17:07,440 But most notes in circulation only have tiny amounts of cocaine on them. 272 00:17:07,440 --> 00:17:11,920 So It is the abnormally high readings that PC Parsons looks for. 273 00:17:11,920 --> 00:17:15,560 And it isn't just bank notes that he is interested in testing. 274 00:17:20,920 --> 00:17:24,400 The police squad visit randomly selected pubs and clubs... 275 00:17:24,400 --> 00:17:26,720 with the full support of the licensees... 276 00:17:26,720 --> 00:17:28,280 to do spot checks with a mobile cocaine scanner 277 00:17:28,280 --> 00:17:32,600 that can detect tiny amounts of the drug on someone's hand. 278 00:17:34,560 --> 00:17:38,320 Anyone that wants to stay in the pub has to agree to be tested. 279 00:17:38,320 --> 00:17:41,720 And those that test positive get questioned and searched. 280 00:17:45,560 --> 00:17:49,280 There are two bags on the floor and very high traces of cocaine on your hands. 281 00:17:49,280 --> 00:17:52,840 I wouldn't drink too much more of that, mate. 282 00:17:52,840 --> 00:17:57,000 'In relation to what has happened in here now, we walked in the door 283 00:17:57,000 --> 00:18:01,080 'and naturally when I walk in if there are people playing pool look at the pool table, 284 00:18:01,080 --> 00:18:02,840 'look at them, have a quick scan around' 285 00:18:02,840 --> 00:18:03,960 and there was nothing on the floor. 286 00:18:03,960 --> 00:18:07,480 I have gone to the bar, to turn round and watch these two 287 00:18:07,480 --> 00:18:09,680 and they have walked around the back here and they have bent down 288 00:18:09,680 --> 00:18:11,200 as if to load the table 289 00:18:11,200 --> 00:18:15,480 and other officers looked and there are two bags of cocaine. 290 00:18:15,480 --> 00:18:18,760 The chap, I have scanned his hand with mobile trace. 291 00:18:18,760 --> 00:18:21,720 He has come up with significant reading of cocaine on his hands. 292 00:18:21,720 --> 00:18:25,120 I have come round here and on the floor is what I believe to be a wrap of cocaine. 293 00:18:25,120 --> 00:18:29,280 I would say it's half a gram of cocaine, probably around £20, £25 worth. 294 00:18:32,840 --> 00:18:38,680 The incredible growth of cocaine into all sections of society began in the 1960s. 295 00:18:38,680 --> 00:18:45,120 It was catapulted into infamy when the drug took a starring role in the Hollywood blockbuster Easy Rider. 296 00:18:45,120 --> 00:18:49,880 It became the drug of the moment and there was an explosion in demand, 297 00:18:49,880 --> 00:18:54,440 which was met by an explosion in supply from South America. 298 00:18:56,640 --> 00:18:59,800 An international supply chain sprang up and drug smugglers 299 00:18:59,800 --> 00:19:01,520 became household names. 300 00:19:01,520 --> 00:19:03,880 The biggest drug lord of them all, 301 00:19:03,880 --> 00:19:10,880 Pablo Escobar, was said to be one of the richest men in the world, making millions of dollars every day. 302 00:19:20,600 --> 00:19:25,160 But the cocaine business has expanded its product range since Escobar's day. 303 00:19:25,160 --> 00:19:27,160 Now there is cocaine for every budget. 304 00:19:31,560 --> 00:19:35,280 This stuff here is like £40 a gram. 305 00:19:35,280 --> 00:19:36,400 You can tell the difference because 306 00:19:36,400 --> 00:19:41,080 this is more powdery, whereas this stuff here which is £80 a gram, 307 00:19:41,080 --> 00:19:47,440 the good stuff is really rocky, and you can see a little shine in it. 308 00:19:50,160 --> 00:19:52,360 Just chop it up. 309 00:19:56,160 --> 00:19:59,320 That's the good stuff, you can taste the difference. 310 00:19:59,320 --> 00:20:03,320 That cheap stuff, it kind of hurts your nose. 311 00:20:03,320 --> 00:20:07,760 This stuff doesn't at all, it just goes up there nice and smoothly. 312 00:20:07,760 --> 00:20:12,800 Snorting too much of any type of coke can harm the nose. 313 00:20:12,800 --> 00:20:15,640 As it hits the delicate lining inside the nostril, 314 00:20:15,640 --> 00:20:18,680 it causes the blood vessels to constrict and shut down, 315 00:20:18,680 --> 00:20:21,120 depriving the tissue of blood and oxygen. 316 00:20:22,640 --> 00:20:26,400 Eventually, the tissue weakens and dies. 317 00:20:26,400 --> 00:20:30,200 This can cause a hole or perforation to develop in the nose. 318 00:20:33,280 --> 00:20:36,800 An operation is often required to repair this damage. 319 00:20:38,320 --> 00:20:39,960 Consultant surgeon Sandeep Paun 320 00:20:39,960 --> 00:20:42,440 is a leading specialist in nose reconstruction. 321 00:20:44,920 --> 00:20:49,520 His patient today made a hole in his nose through regular cocaine use. 322 00:20:49,520 --> 00:20:52,240 He's asked to be kept anonymous. 323 00:20:52,240 --> 00:20:55,560 As you know, we are going to be sorting out your nasal septum perforation today. 324 00:20:55,560 --> 00:20:58,440 When was the last time you used it regularly? 325 00:20:58,440 --> 00:21:03,560 Regularly, six months previous. 326 00:21:03,560 --> 00:21:08,440 OK. There are certainly no guarantees we can close the perforation completely. 327 00:21:08,440 --> 00:21:14,880 Certainly after cocaine use, closure of septal perforations is difficult. 328 00:21:14,880 --> 00:21:16,280 I only found out about the hole 329 00:21:16,280 --> 00:21:21,760 when I went to the doctor's and he pulled a scab out of the nose, 330 00:21:21,760 --> 00:21:25,520 which covered the hole, which then became really scary. 331 00:21:25,520 --> 00:21:29,360 When you look at Danniella Westbrook, once you see what happened to her, 332 00:21:29,360 --> 00:21:30,640 her nose actually collapsed 333 00:21:30,640 --> 00:21:35,080 and the scariest thing is that you think its going to happen to you. 334 00:21:35,080 --> 00:21:39,680 The operation requires the patient's nose to be cut open and split in two. 335 00:21:39,680 --> 00:21:42,200 The images can be very graphic. 336 00:21:42,200 --> 00:21:45,160 We're just going to look in this gentleman's nose now. 337 00:21:46,200 --> 00:21:49,960 We're going through the nostrils, having a look inside. 338 00:21:49,960 --> 00:21:53,640 What we can see at the front of the septum is the hole. 339 00:21:53,640 --> 00:21:59,320 It's actually relatively small for a patient who has had cocaine abuse. 340 00:21:59,320 --> 00:22:01,920 You would expect to see it much larger than this. 341 00:22:01,920 --> 00:22:06,000 Often these perforations can progress way beyond the size we see here. 342 00:22:06,000 --> 00:22:08,360 Knife, please. 343 00:22:08,360 --> 00:22:13,120 Sometimes doing it you would take a line and you would have 344 00:22:13,120 --> 00:22:19,200 a real bad burning sensation from the start of your nose right the way through to the back of your throat, 345 00:22:19,200 --> 00:22:20,640 really painful. 346 00:22:20,640 --> 00:22:24,800 The next day when you wake up you have scabs 347 00:22:24,800 --> 00:22:30,760 and there's parts of your nose you are actually blowing out. 348 00:22:30,760 --> 00:22:33,720 With chronic cocaine abuse, 349 00:22:33,720 --> 00:22:35,560 as the perforation gets bigger and bigger, 350 00:22:35,560 --> 00:22:38,680 the cartilage gets weaker and weaker because there 351 00:22:38,680 --> 00:22:40,000 is not enough support 352 00:22:40,000 --> 00:22:45,040 and as the top of the nose begins to collapse, one can end up with a boxer-type appearance. 353 00:22:45,040 --> 00:22:47,640 Scissors please. 354 00:22:47,640 --> 00:22:51,040 I have seen patients where the whole middle of the nose has gone 355 00:22:51,040 --> 00:22:54,880 and you just have one nasal cavity and everything just collapses inwards. 356 00:22:54,880 --> 00:22:59,000 I was doing it every day of the week. It doesn't worry you at the time when 357 00:22:59,000 --> 00:23:04,760 you are doing it obviously, but afterwards, your nose is sore as hell, 358 00:23:04,760 --> 00:23:10,640 times when you nose is bleeding it makes you have regrets doing it in the first place. 359 00:23:10,640 --> 00:23:18,440 OK, so what we see here, inside the nose, is the lining on one side, you can see 360 00:23:18,440 --> 00:23:22,160 the hole through the lining, so initially cocaine would have created 361 00:23:22,160 --> 00:23:25,520 a hole in the lining but not through the cartilage, 362 00:23:25,520 --> 00:23:30,520 but eventually it will have worked its way through the cartilage and eventually through the other side. 363 00:23:30,520 --> 00:23:35,360 The fact that cocaine is mixed with all sorts of contaminants including 364 00:23:35,360 --> 00:23:40,840 baking soda, glucose and in the worst case scenario even talcum powder, 365 00:23:40,840 --> 00:23:44,680 can cause an intense inflammatory response. 366 00:23:44,680 --> 00:23:49,040 This inflammation can cause the flesh in the nose to die even more rapidly 367 00:23:51,120 --> 00:23:58,520 Ironically, Mr Paun actually administers cocaine to the patient to stop bleeding. 368 00:23:58,520 --> 00:24:03,720 Patients don't snort it up beforehand or anything, but we give them a small amount 369 00:24:03,720 --> 00:24:05,840 in liquid form. 370 00:24:08,160 --> 00:24:12,800 I'm just taking out a little bead of cartilage, from the back end 371 00:24:12,800 --> 00:24:17,840 of the nasal septum which we are then going to replace the front end with. 372 00:24:17,840 --> 00:24:21,800 The bit of cartilage is going to close off the hole. 373 00:24:28,600 --> 00:24:32,800 So you can see on one side here, the lining has been completely closed 374 00:24:32,800 --> 00:24:34,960 where there was a hole before. 375 00:24:34,960 --> 00:24:36,640 As we look on the other side, 376 00:24:36,640 --> 00:24:39,840 similarly there is no hole there now. 377 00:24:40,680 --> 00:24:44,440 I run a fairly specialist nasal practice in the city of London 378 00:24:44,440 --> 00:24:47,080 where there is a lot of money floating around. 379 00:24:47,080 --> 00:24:52,000 I must see a patient every few weeks with nasal problems related to cocaine exposure. 380 00:24:57,120 --> 00:25:01,280 City high fliers and cocaine have been synonymous for decades. 381 00:25:01,280 --> 00:25:05,040 The drug became the ultimate status symbol in the booming '80s 382 00:25:05,040 --> 00:25:07,880 when greed was good and bankers were heroes. 383 00:25:07,880 --> 00:25:12,240 It was the champagne drug, a sophisticated show of extravagance. 384 00:25:12,240 --> 00:25:17,480 But in the middle of this cocaine honeymoon a new form of the drug appeared - crack. 385 00:25:23,280 --> 00:25:26,840 See this cute little vial here - it's crack. Rock cocaine. 386 00:25:26,840 --> 00:25:29,000 The most addictive form. 387 00:25:29,000 --> 00:25:31,120 You think it's the glamour drug of the '80s? 388 00:25:31,120 --> 00:25:33,400 That's the point of this little reminder. 389 00:25:33,400 --> 00:25:39,720 It can kill you. And if you've got to die for something, this sure as hell ain't it. 390 00:25:41,040 --> 00:25:45,040 Crack is simply another form of cocaine that is smoked rather than snorted. 391 00:25:45,040 --> 00:25:48,920 Because the surface area of the lungs is much bigger 392 00:25:48,920 --> 00:25:51,640 than that of the membranes in the nose, the drug is absorbed 393 00:25:51,640 --> 00:25:56,880 much more quickly, making the hit faster and more intense. 394 00:25:56,880 --> 00:26:03,080 The speed and intensity of the hit makes it much more addictive. 395 00:26:03,080 --> 00:26:05,800 The press and politicians warned of an epidemic. 396 00:26:05,800 --> 00:26:08,400 Crack became the number one public enemy. 397 00:26:08,400 --> 00:26:12,840 The Home Secretary, Douglas Hurd, has described the cocaine-based drug, crack, 398 00:26:12,840 --> 00:26:14,920 as "a spectre hanging over Europe." 399 00:26:14,920 --> 00:26:21,080 The high from crack is so powerful, its users can become totally consumed by the drug. 400 00:26:21,080 --> 00:26:24,080 It becomes more important than eating or washing, 401 00:26:24,080 --> 00:26:28,320 and this leads to a rapid deterioration in addicts' health and appearance. 402 00:26:28,320 --> 00:26:34,040 Dramatic drug awareness campaigns showed the damage it could do. 403 00:26:34,040 --> 00:26:38,400 Crack became associated with drug addicts and poverty. 404 00:26:38,400 --> 00:26:42,800 But this didn't dent the unassailable glamorous image of powder cocaine, 405 00:26:42,800 --> 00:26:45,160 which remained in massive demand. 406 00:26:45,160 --> 00:26:52,320 This led to trafficking on a vast scale and the price to fall from £150 to £50 a gram. 407 00:26:53,920 --> 00:26:56,840 As the amount of cocaine imported into Britain has soared, 408 00:26:56,840 --> 00:27:01,200 the purity on the street has fallen dramatically. 409 00:27:01,200 --> 00:27:07,200 No-one knows this better than the Forensic Science Service. 410 00:27:07,200 --> 00:27:10,280 They analyse the purity of cocaine seized by customs and the police 411 00:27:10,280 --> 00:27:13,040 to gather vital intelligence about the supply chain. 412 00:27:15,520 --> 00:27:19,640 The purer the seizure, the closer its source will be to the importer. 413 00:27:20,800 --> 00:27:23,720 We're in the main storage area of the drugs laboratory. 414 00:27:23,720 --> 00:27:27,120 This is where the main seizures are stored while they are being examined. 415 00:27:27,120 --> 00:27:30,760 Approximately 80% of the drugs in this room are cocaine. 416 00:27:34,920 --> 00:27:37,040 On a typical day this lab, one of seven across Britain, 417 00:27:37,040 --> 00:27:41,320 will examine 100 kg of cocaine worth £50 million pounds. 418 00:27:41,320 --> 00:27:44,840 Just a small fraction of the three tonnes, 419 00:27:44,840 --> 00:27:51,200 worth 1.5 billion pounds, that was seized in the UK between 2008 and 2009. 420 00:27:54,560 --> 00:27:59,040 Cocaine seized as it is being smuggled into Britain is relatively pure. 421 00:27:59,040 --> 00:28:03,400 This is a bag of approximately 1kg of cocaine powder, 422 00:28:03,400 --> 00:28:08,000 It contains 79% cocaine and is good importation quality. 423 00:28:09,600 --> 00:28:12,960 But when the FSS test cocaine from the street, 424 00:28:12,960 --> 00:28:17,800 seized from dealers and users, they find it is much less pure. 425 00:28:17,800 --> 00:28:22,880 The typical street range of cocaine is perhaps 3 to 30%, commonly 10 to 20%. 426 00:28:22,880 --> 00:28:27,360 We have seen cocaine powders containing perhaps only 1% cocaine. 427 00:28:28,880 --> 00:28:33,200 Dealers cut cocaine with bulking agents to increase their profit margin. 428 00:28:33,200 --> 00:28:38,480 Most of the white powder sold as cocaine is actually made up of something else that looks like it - 429 00:28:38,480 --> 00:28:43,920 sugars such as lactose or glucose, or anaesthetics such as benzocaine or lignocaine. 430 00:28:43,920 --> 00:28:48,000 The benzocaine and lignocaine will mimic the effects of cocaine 431 00:28:48,000 --> 00:28:50,280 in terms of, if you test it, 432 00:28:50,280 --> 00:28:54,360 cocaine will give you a numbing effect, benzocaine and lignocaine will do likewise. 433 00:28:54,360 --> 00:28:58,200 Just by sight, you are not going to know what the quality of the cocaine is, 434 00:28:58,200 --> 00:29:02,480 and you may not know what is present in the powder before you buy it. 435 00:29:06,680 --> 00:29:11,200 As the night progresses, the Bristol house party is in full flow. 436 00:29:11,200 --> 00:29:16,600 The high from even relatively pure cocaine only lasts for 30 or 40 minutes, 437 00:29:16,600 --> 00:29:20,720 so Damian has been working his way through his supplies. 438 00:29:20,720 --> 00:29:25,440 Must be about 11 o'clock now. Yeah, I've done about four or five lines. 439 00:29:25,440 --> 00:29:32,080 It's very more-ish. You just want to do more and more, cos the effect wears away quite quickly, 440 00:29:32,080 --> 00:29:35,480 so you have another line and another line. 441 00:29:35,480 --> 00:29:38,720 As the cocaine travels around the body in the blood, 442 00:29:38,720 --> 00:29:43,120 it passes through the liver, which begins to process and break down the drug. 443 00:29:43,120 --> 00:29:48,680 After 30 minutes, half the cocaine has been broken down, and the high is over. 444 00:29:48,680 --> 00:29:54,560 This process happens much more quickly with cocaine than with other drugs, such as cannabis or ecstasy. 445 00:29:54,560 --> 00:29:59,640 To keep feeling good on coke, people have to keep doing more lines. 446 00:29:59,640 --> 00:30:04,040 This can lead to people bingeing on it, with serious consequences. 447 00:30:04,040 --> 00:30:07,880 'The most coke I've done was in a club in Bristol.' 448 00:30:07,880 --> 00:30:11,600 We had literally done about an eighth between the three of us before, 449 00:30:11,600 --> 00:30:16,880 and then I had a gram left, and I just thought I might as well, the coke wasn't that good. 450 00:30:16,880 --> 00:30:21,720 So I snuck into the bathroom, took a line of coke that big, 451 00:30:21,720 --> 00:30:23,320 it was a gram. 452 00:30:23,320 --> 00:30:26,280 If it was good coke, I would probably have died, 453 00:30:26,280 --> 00:30:30,960 but as soon as I took it, my heart raced, I started to sweat so much, 454 00:30:30,960 --> 00:30:34,240 and, literally, I couldn't stand up any more. 455 00:30:34,240 --> 00:30:37,200 I had to lie down for at least half an hour. 456 00:30:37,200 --> 00:30:40,680 Damian's heart was racing after his huge line 457 00:30:40,680 --> 00:30:43,920 because it is not just the brain where cocaine has an effect. 458 00:30:47,640 --> 00:30:52,720 The drug also directly stimulates nerve cells in the heart to produce noradrenaline, 459 00:30:52,720 --> 00:30:56,200 from their tips straight into the muscle fibres. 460 00:30:57,960 --> 00:31:02,400 This normally happens when you're in danger, to make your heart beat faster, 461 00:31:02,400 --> 00:31:05,200 so that you can fight or get away from trouble. 462 00:31:05,200 --> 00:31:09,600 It also causes blood vessels to squeeze and constrict. 463 00:31:09,600 --> 00:31:12,280 Blood pressure starts to rise. 464 00:31:12,280 --> 00:31:15,680 Cocaine increases your pulse rate and your blood pressure 465 00:31:15,680 --> 00:31:18,000 and it makes your heart beat more quickly. 466 00:31:18,000 --> 00:31:21,920 All of those things mean that your heart needs an increased blood supply. 467 00:31:21,920 --> 00:31:25,360 It needs more oxygen to beat more quickly and beat more strongly. 468 00:31:25,360 --> 00:31:28,920 Unfortunately, what cocaine does is, it also causes constriction 469 00:31:28,920 --> 00:31:31,840 of those blood vessels that supply blood to the heart. 470 00:31:31,840 --> 00:31:36,280 It's like putting your foot on the accelerator and pinching the fuel line. 471 00:31:36,280 --> 00:31:40,680 The heart is starved of the oxygen it desperately needs to beat faster, 472 00:31:40,680 --> 00:31:42,800 putting it under enormous strain. 473 00:31:42,800 --> 00:31:44,920 This can cause a heart attack. 474 00:31:44,920 --> 00:31:48,120 In the first hour after taking cocaine, 475 00:31:48,120 --> 00:31:52,120 the risk of having a heart increases by 20 fold. 476 00:31:52,120 --> 00:31:59,000 Cocaine also causes the build up of plaque in blood vessels over long periods, just like fatty foods. 477 00:31:59,000 --> 00:32:03,120 This plaque can tear, causing a blood clot to form, 478 00:32:03,120 --> 00:32:07,000 blocking the artery, causing a heart attack at any time. 479 00:32:07,000 --> 00:32:13,200 About a quarter of heart attacks among people under 45 years of age are cocaine related. 480 00:32:17,320 --> 00:32:20,720 It doesn't take much cocaine to affect the heart's function - 481 00:32:20,720 --> 00:32:23,120 a couple of lines can have a massive impact. 482 00:32:23,120 --> 00:32:28,560 Even occasional users can have problems, taking them by surprise. 483 00:32:30,960 --> 00:32:34,440 Tom is a 19-year-old musician who lives in Portsmouth. 484 00:32:34,440 --> 00:32:38,800 He started taking cocaine a couple of years ago. 485 00:32:38,800 --> 00:32:43,640 I was just at a party and, literally, someone was doing it and they just said, 486 00:32:43,640 --> 00:32:47,880 "Do you want that one?" And I just went, "Yeah, OK." 487 00:32:47,880 --> 00:32:51,960 I was just really chatting and just full of energy. 488 00:32:51,960 --> 00:32:55,520 And just like, "Whoa!" Do you know what I mean? 489 00:33:00,760 --> 00:33:02,320 From that party, 490 00:33:02,320 --> 00:33:07,760 it became a thing where I would do it a few times a week, mostly at the weekends. 491 00:33:07,760 --> 00:33:11,400 I was probably taking about a gram over the course of a weekend. 492 00:33:19,880 --> 00:33:22,320 Tom started to get occasional chest pains, 493 00:33:22,320 --> 00:33:26,040 so he went to a doctor, who told him it was indigestion. 494 00:33:26,040 --> 00:33:32,800 A few weeks later, I was having a gathering with my friends, got some coke, took it, thought nothing of it. 495 00:33:32,800 --> 00:33:37,160 The next day, Tom visited London with his family 496 00:33:37,160 --> 00:33:41,640 I'd had this pain in my arm all day, but I didn't take notice of it. Then, all of a sudden, 497 00:33:41,640 --> 00:33:44,560 pain shot up my arm and my chest started going tight 498 00:33:44,560 --> 00:33:49,600 and then I lost my breath. I tapped my mum on the shoulder to try to get her attention. 499 00:33:49,600 --> 00:33:53,000 I couldn't hear or feel nothing. It was like everything was on mute 500 00:33:53,000 --> 00:33:56,120 and I was just looking at life, but without being in it. 501 00:33:56,120 --> 00:34:00,160 And then I just had this breath come up and I went, "I need to go to hospital." 502 00:34:00,160 --> 00:34:04,160 Then it was straight through to the emergency rooms, 503 00:34:04,160 --> 00:34:08,080 in a bed with your oxygen mask, with your heart wired up, 504 00:34:08,080 --> 00:34:11,040 with needle in your arm, fluids going in. 505 00:34:11,040 --> 00:34:14,880 Everything they had to keep me going was on. 506 00:34:14,880 --> 00:34:19,160 Absolutely terrified. It was the scariest thing that's ever happened to me 507 00:34:22,160 --> 00:34:26,800 The cocaine that Tom had taken caused a clot to form, blocking blood getting to his heart. 508 00:34:26,800 --> 00:34:31,920 It slowed to just 28 beats per minute and he had a heart attack. 509 00:34:31,920 --> 00:34:35,960 What have I done? That was my exact question to myself. 510 00:34:35,960 --> 00:34:37,320 What have I done? 511 00:34:37,320 --> 00:34:42,240 I didn't realise the effect that anything would have on people 512 00:34:42,240 --> 00:34:46,040 until you're there in... what you could say a death-bed, basically... 513 00:34:46,040 --> 00:34:48,600 It could have been your death bed. 514 00:34:48,600 --> 00:34:50,680 ..with family next to you, in tears. 515 00:34:50,680 --> 00:34:53,240 The scariest thing ever. 516 00:34:53,240 --> 00:34:56,560 There's nothing worse than thinking that you could be dead, 517 00:34:56,560 --> 00:35:00,080 cos that's the end. Once you're gone, you're gone. 518 00:35:00,080 --> 00:35:03,360 The damage to Tom's heart meant that, at just 17 years old, 519 00:35:03,360 --> 00:35:06,560 he would need a pacemaker to regulate his heartbeat. 520 00:35:06,560 --> 00:35:08,480 That's the battery. 521 00:35:08,480 --> 00:35:12,280 Then the wire, um, actually comes up here 522 00:35:12,280 --> 00:35:16,800 and then it goes round and then it goes into your heart 523 00:35:16,800 --> 00:35:19,440 and into the chambers that aren't working, 524 00:35:19,440 --> 00:35:22,040 and it gives that, um, electrical shock 525 00:35:22,040 --> 00:35:26,600 that it needs to work properly. 526 00:35:26,600 --> 00:35:28,280 It's in there for ever. 527 00:35:28,280 --> 00:35:30,240 Without that, I'm not... 528 00:35:30,240 --> 00:35:32,880 I'm not here. 529 00:35:34,400 --> 00:35:38,120 Although still rare, the number of cocaine-related deaths in Britain 530 00:35:38,120 --> 00:35:43,680 has increased five times in the last decade, as cocaine use has become more common. 531 00:35:43,680 --> 00:35:46,080 But cocaine maintains its appeal 532 00:35:46,080 --> 00:35:51,040 and users take even greater risks by mixing it with other substances, like alcohol. 533 00:35:54,760 --> 00:35:57,320 INDISTINCT CHATTER 534 00:36:00,200 --> 00:36:04,360 For Liam, drinking and cocaine go hand in hand. 535 00:36:04,360 --> 00:36:07,800 He and his friends are at their local for a session. 536 00:36:13,720 --> 00:36:16,720 'I don't have it unless I've been drinking as well.' 537 00:36:16,720 --> 00:36:20,520 I couldn't just sniff coke ever, no chance. I wouldn't do it. 538 00:36:20,520 --> 00:36:24,720 'You always want a beer after, or you want to be drunk before you have some.' 539 00:36:24,720 --> 00:36:28,640 Drinking, it's a must for me. And for most people. 540 00:36:28,640 --> 00:36:33,840 Many share Liam's view. 61% of people that take cocaine drink at the same time. 541 00:36:33,840 --> 00:36:39,000 One of the side effects of cocaine is that people can feel a bit anxious, 542 00:36:39,000 --> 00:36:45,160 a little bit too jittery, and consuming alcohol kind of turns the volume down on that. 543 00:36:45,160 --> 00:36:47,880 So it can reduce that anxiety and that twitchiness. 544 00:36:47,880 --> 00:36:49,760 Ryan does a line. 545 00:36:54,120 --> 00:36:55,400 < How does it feel? 546 00:36:55,400 --> 00:36:57,120 That feels good, man. 547 00:36:57,120 --> 00:36:58,800 < On top of the world! 548 00:36:58,800 --> 00:37:04,120 Say if you've been drinking all day and you have a line, it helps you out, you know? 549 00:37:04,120 --> 00:37:06,480 I think it feels better. 550 00:37:08,360 --> 00:37:14,120 When users drink and take coke at the same time, their liver forms a chemical called cocaethylene. 551 00:37:14,120 --> 00:37:20,120 This cocaethylene is pumped through the blood up to the brain, where, like cocaine, 552 00:37:20,120 --> 00:37:24,200 it also causes the release of dopamine, making users high. 553 00:37:24,200 --> 00:37:28,520 The effects are quite similar to cocaine - there's euphoria, 554 00:37:28,520 --> 00:37:33,480 confidence, talkativeness, but the effects last a lot longer. 555 00:37:35,320 --> 00:37:40,800 The high from cocaethylene can make people feel less anxious than just cocaine... 556 00:37:42,840 --> 00:37:45,880 ..but it also stimulates nerve cells in the heart 557 00:37:45,880 --> 00:37:50,840 to produce lots of noradrenaline, making it beat three times faster than cocaine alone. 558 00:37:52,360 --> 00:37:57,160 The blood vessels get even tighter, and blood pressure shoots up, 559 00:37:57,160 --> 00:38:02,000 making users much more likely to die from a heart attack than taking cocaine on its own. 560 00:38:04,960 --> 00:38:07,760 The risks from mixing coke and booze are all the worse 561 00:38:07,760 --> 00:38:12,360 because cocaine allows users to drink far more than they normally would. 562 00:38:14,040 --> 00:38:18,720 Half of regular users drank for more than 12 hours on their last night out on cocaine, 563 00:38:18,720 --> 00:38:22,040 and a third for more than 24 hours. 564 00:38:22,040 --> 00:38:25,960 If you've been sniffing, you can drink loads. You're not pissed. You're up, 565 00:38:25,960 --> 00:38:29,080 You're on a stimulant. Beer is a bit more of a downer. 566 00:38:29,080 --> 00:38:32,400 These prolonged sessions not only put the heart under strain, 567 00:38:32,400 --> 00:38:38,080 the quantity of alcohol consumed can also harm the rest of the body. 568 00:38:38,080 --> 00:38:42,800 You can drink all night. I suppose it's bad. If you don't realise what you're drinking, then... 569 00:38:43,280 --> 00:38:44,960 THEY CHATTER 570 00:38:44,960 --> 00:38:49,200 For many, coke has become nothing more than a pick-me-up with their pint, 571 00:38:49,200 --> 00:38:51,040 but it could get them arrested. 572 00:38:52,720 --> 00:38:56,440 Back in Kent, the police drug squad are moving onto a nightclub 573 00:38:56,440 --> 00:39:01,200 and are set to be busy, because it's night-time when the cocaine detector gets the most hits. 574 00:39:09,000 --> 00:39:16,640 'Cocaine is everywhere. It's seen as a recreational drug, so to speak, and people use it quite openly.' 575 00:39:16,640 --> 00:39:20,440 I think cocaine is so popular because it is so easy to get hold of. 576 00:39:20,440 --> 00:39:23,320 It's probably even easier than cannabis to get hold of. 577 00:39:23,320 --> 00:39:25,560 Can I check your hands, please? 578 00:39:25,560 --> 00:39:27,360 Just give me your hand. 579 00:39:28,760 --> 00:39:30,600 Ever used drugs? 580 00:39:30,600 --> 00:39:35,040 People that want to come into the club this evening have to agree to a hand scan. 581 00:39:35,040 --> 00:39:39,680 When we do these operations, we would normally test between 200 and 300 people a night. 582 00:39:39,680 --> 00:39:47,440 Out of those 200 or 300, probably 30-ish would come up with significant traces of cocaine on their hands, 583 00:39:47,440 --> 00:39:49,440 and following on from that, 584 00:39:49,440 --> 00:39:55,080 probably anywhere between two and seven or eight of those 30 would have cocaine on them. 585 00:39:55,080 --> 00:40:01,960 83% of clubbers surveyed across the country said they had used cocaine in the last year. 586 00:40:01,960 --> 00:40:04,400 When did you last use cocaine? Yesterday. 587 00:40:04,400 --> 00:40:06,760 Thanks for being honest. Makes it easier. 588 00:40:06,760 --> 00:40:10,800 Have you used cocaine? Yesterday night was the last time. Yesterday night? 589 00:40:10,800 --> 00:40:15,760 You sure? Yes. I'm going to give you a search, OK? 590 00:40:15,760 --> 00:40:17,960 What's your name? Joe. 591 00:40:17,960 --> 00:40:23,440 Many more people test positive for cocaine than are found in possession of the drug. 592 00:40:27,360 --> 00:40:30,120 You've got exceptionally high traces of cocaine... 593 00:40:30,120 --> 00:40:32,960 The people that trigger high readings on the scanner 594 00:40:32,960 --> 00:40:36,160 but don't have any cocaine on them haven't broken the law, 595 00:40:36,160 --> 00:40:40,840 but they are refused entry to the club and ordered to go home for the night. 596 00:40:42,680 --> 00:40:48,360 As the evening wears on, the scanner keeps getting hit after hit, and the searches continue. 597 00:40:48,360 --> 00:40:52,240 Do you understand the reason why I'm searching you? For drugs. 598 00:40:52,240 --> 00:40:54,640 Have you got any drugs on you? No, Officer. 599 00:40:54,640 --> 00:40:56,480 The stakes are high. 600 00:40:56,480 --> 00:41:00,440 People that are found with cocaine on them could face jail. 601 00:41:00,440 --> 00:41:05,520 What is this, then? That's a bit of powder, mate. Tell me what it is. Cocaine. 602 00:41:05,520 --> 00:41:08,920 Have you got any more on you? No... Eh? 603 00:41:08,920 --> 00:41:10,600 What's that, then? 604 00:41:10,600 --> 00:41:13,040 Put your hand out. Keep your hand out. 605 00:41:16,960 --> 00:41:18,880 Are you arresting me? 606 00:41:18,880 --> 00:41:22,520 POLICEMAN READS RIGHTS That's fine. 607 00:41:22,520 --> 00:41:25,440 Do you understand the reason why you've been arrested? 608 00:41:25,440 --> 00:41:30,320 Yes, I do, Officer. Is there anything you want to say? So much for a decent birthday, eh? 609 00:41:30,320 --> 00:41:33,960 This man later pleaded guilty to possession of cocaine. 610 00:41:33,960 --> 00:41:39,920 Because he had a relatively small amount and it was his first offence, he avoided a custodial sentence. 611 00:41:39,920 --> 00:41:45,200 Cocaine use has gone up, without a shadow of a doubt, over the last ten years, quite a lot. 612 00:41:45,200 --> 00:41:48,240 'Out of rehab and straight into serious trouble, 613 00:41:48,240 --> 00:41:51,160 'Lindsay Lohan seems to be out of control.' 614 00:41:51,160 --> 00:41:55,440 We also found a small amount of cocaine in her pocket. 615 00:41:55,440 --> 00:42:00,040 Despite becoming widespread, cocaine remains a newsworthy story. 616 00:42:00,040 --> 00:42:04,160 'Singer Pete Doherty has pleaded guilty to possessing cocaine. 617 00:42:04,160 --> 00:42:06,880 'Magistrates were told the drugs were found in his car.' 618 00:42:06,880 --> 00:42:10,760 Every time a famous person gets caught snorting a line or in possession, 619 00:42:10,760 --> 00:42:13,480 it's guaranteed to make headlines. 620 00:42:13,480 --> 00:42:19,320 A UN report blamed celebrity cocaine culture for making the drug socially acceptable in Britain. 621 00:42:19,320 --> 00:42:22,800 In the UK, we take more than people in America, 622 00:42:22,800 --> 00:42:24,880 or anywhere else in Europe. 623 00:42:36,200 --> 00:42:40,760 As the number of people that take coke have gone up, rates of addiction have soared. 624 00:42:40,760 --> 00:42:44,600 Sometimes when it starts to wear off, you feel like you want another line, 625 00:42:44,600 --> 00:42:46,320 but that depends on the person. 626 00:42:46,320 --> 00:42:49,400 Some people have addictive personalities. I don't. 627 00:42:49,400 --> 00:42:55,720 When you first start doing coke it's very addictive. You annihilate it and take it to the extremes. 628 00:42:55,720 --> 00:42:59,960 These days, I don't take coke that often. 629 00:42:59,960 --> 00:43:05,680 But last year I was taking it pretty much every day. 630 00:43:05,680 --> 00:43:09,160 Now it would be special occasions going out. 631 00:43:14,200 --> 00:43:17,400 When I did take it, often you're just chasing that high all the time. 632 00:43:17,400 --> 00:43:23,520 It was difficult to stop doing it because you're doing it all the time but now I enjoy it more 633 00:43:23,520 --> 00:43:25,240 because it's much more sporadic. 634 00:43:27,120 --> 00:43:32,040 One of the unusual things about cocaine is, I think it does tend to creep up on people. 635 00:43:32,040 --> 00:43:38,480 People can use cocaine intranasally, snorting it, for many months and years 636 00:43:38,480 --> 00:43:42,320 within what they would consider quite a functional social setting. 637 00:43:42,320 --> 00:43:47,320 Gradually, the amount and frequency and the consequences of use build up. 638 00:43:47,320 --> 00:43:53,320 Cocaine is powerfully addictive, but the need to use is psychological, not physical. 639 00:43:53,320 --> 00:43:55,960 Addicts become obsessed with the cocaine high. 640 00:43:55,960 --> 00:44:01,160 There's a sense that being addicted to cocaine is a disorder of memory. 641 00:44:01,160 --> 00:44:09,040 The world becomes a place in which people, places, objects, even smells 642 00:44:09,040 --> 00:44:13,400 have become quite strongly associated with using cocaine. 643 00:44:13,400 --> 00:44:18,920 And they become very powerful triggers to make the person use. 644 00:44:18,920 --> 00:44:26,000 About 1 person in 20 who takes the drug for the first time becomes addicted in the first year. 645 00:44:26,000 --> 00:44:30,360 And about a fifth of users become addicted in their lifetime. 646 00:44:35,800 --> 00:44:38,840 Soon after getting a job in the city as a money broker, 647 00:44:38,840 --> 00:44:42,160 Jonathan developed a serious addiction to cocaine. 648 00:44:45,040 --> 00:44:50,160 My first line ever, it just blew me away. 649 00:44:50,160 --> 00:44:54,480 I was strutting round thinking I'm Billy Big-bollocks, thinking I own the place. 650 00:44:54,480 --> 00:44:59,120 It made me feel like I was the most important person in the room. 651 00:44:59,120 --> 00:45:03,680 And it very quickly progressed from half a gram every couple of weeks, 652 00:45:03,680 --> 00:45:08,880 to a gram every week, to two grams three times a week, 653 00:45:08,880 --> 00:45:13,080 then suddenly I might be going out every night of the week 654 00:45:13,080 --> 00:45:17,680 and I would come into work on a Monday saying, "Oh, heavy weekend - might have a light one tonight" 655 00:45:17,680 --> 00:45:22,200 and it gets to five o'clock and someone says, "Jon, you coming for a quick one?" 656 00:45:22,200 --> 00:45:24,280 I say, "Yeah, just a quick one, that's not a problem." 657 00:45:24,280 --> 00:45:29,000 Go to bar, have a quick one. Quick one turns into four. There's a guy on his way 658 00:45:29,000 --> 00:45:33,240 because the phones have come out and there's a bit of powder going round. 659 00:45:33,240 --> 00:45:38,240 We go from pub to bar, then from bar to club there's a guy on his way with some more stuff. 660 00:45:38,240 --> 00:45:42,480 Then back to the office, we would be in the smoking room, on the dealing-room floor, 661 00:45:42,480 --> 00:45:45,320 doing line after line off the table. 662 00:45:45,320 --> 00:45:49,360 Well, I'D be doing line after line, that's the thing. 663 00:45:49,360 --> 00:45:52,760 When I'm using, I think everyone else is behaving like me. 664 00:45:52,760 --> 00:45:55,920 Truth is, when I look back, I am, far and away, the worst. 665 00:45:58,360 --> 00:46:02,440 Get to 5:00 or 6:00am, people start coming into work and it's like... 666 00:46:03,440 --> 00:46:05,400 I've got to go and sit at my desk. 667 00:46:05,400 --> 00:46:08,880 And I've got to try and stay awake and do my job. 668 00:46:08,880 --> 00:46:14,120 I struggle through it, thinking all day, "I've got to go home tonight. 669 00:46:14,120 --> 00:46:16,480 "I got to get some sleep." 670 00:46:16,480 --> 00:46:20,280 Some weeks maybe I wouldn't go home between Monday and Friday. 671 00:46:20,280 --> 00:46:23,120 It would be three, four grams every night I could get it - 672 00:46:23,120 --> 00:46:25,280 six or seven nights a week. 673 00:46:26,800 --> 00:46:30,960 I would take as much as I could afford to buy on any one night. 674 00:46:33,600 --> 00:46:40,520 The repeated exposure to cocaine that an addict's brain is subjected to causes it to physically change. 675 00:46:42,920 --> 00:46:46,400 To regulate the constant triggering of the feel-good network, 676 00:46:46,400 --> 00:46:50,440 the brain kills off some of the receptors on the nerve cells. 677 00:46:50,440 --> 00:46:56,040 With fewer receptors on each nerve cell, it takes much more dopamine to trigger happy feelings... 678 00:46:56,040 --> 00:47:01,240 more than is released by normal sources, such as food or sex. 679 00:47:01,240 --> 00:47:05,320 Only cocaine can release enough dopamine to trigger their feel-good network. 680 00:47:07,320 --> 00:47:12,400 After a while, addicts crave a line not to feel high, but to feel less bad... 681 00:47:12,400 --> 00:47:14,040 more normal. 682 00:47:14,040 --> 00:47:21,200 I did get pleasure from it still, occasionally, but less as time went on, 683 00:47:21,200 --> 00:47:23,200 less each time I did it. 684 00:47:24,720 --> 00:47:27,280 It very quickly fell away. 685 00:47:30,640 --> 00:47:36,560 Until, eventually, I was just doing it because I needed it. 686 00:47:36,560 --> 00:47:39,240 It wasn't making me feel good any more. 687 00:47:44,200 --> 00:47:49,520 Eventually, because I am so petrified every time I am at work that I am going to cock up, 688 00:47:49,520 --> 00:47:54,440 do something wrong, that people don't like me, people think I am an idiot... 689 00:47:54,440 --> 00:48:02,000 I am so petrified that, eventually, I am shaking, having panic attacks, 690 00:48:02,000 --> 00:48:07,240 I've got mad paranoia and I phone in one day and say, "I can't go to work, 691 00:48:07,240 --> 00:48:10,200 "I think I'm having a nervous breakdown." 692 00:48:12,840 --> 00:48:18,960 Signed off work by his doctor on full pay, Jonathan's addiction spiralled out of control. 693 00:48:18,960 --> 00:48:23,280 I isolated more and more and more. 694 00:48:23,280 --> 00:48:25,960 But I keep doing it because it's all I know how to do... 695 00:48:28,000 --> 00:48:31,080 ..so it carries on. 696 00:48:31,080 --> 00:48:33,600 And, er, 697 00:48:33,600 --> 00:48:36,480 some stuff went on, my granddad died 698 00:48:38,000 --> 00:48:44,320 and I couldn't go to be by his bedside because I had to go and use. 699 00:48:44,320 --> 00:48:50,320 A week after that, I manufacture an argument with my family and I end up 700 00:48:50,320 --> 00:48:56,000 fighting my little old mum for money for coke. 701 00:48:57,280 --> 00:49:02,760 I don't want to be doing this but I have to because I have to have it. 702 00:49:03,760 --> 00:49:06,880 They end up pinning me down and phoning the police. 703 00:49:06,880 --> 00:49:10,920 The police are marching me out of my Mum and Dad's house 704 00:49:10,920 --> 00:49:14,800 and we're going down the stairs and I just can't do this any more. 705 00:49:16,320 --> 00:49:18,880 I see a knife in the kitchen, so I slip the guy's grip, 706 00:49:18,880 --> 00:49:22,760 run into the kitchen, grab the knife and slash my wrists up 707 00:49:22,760 --> 00:49:27,280 and the ambulance turns up and they take me to the hospital. 708 00:49:27,280 --> 00:49:32,760 Having reached rock bottom, Jonathan sought help from a support group for cocaine addicts. 709 00:49:32,760 --> 00:49:35,240 I had nowhere else to go. 710 00:49:35,240 --> 00:49:38,360 For me, that's the reality of my addiction. I have to be broken. 711 00:49:38,360 --> 00:49:40,960 I have to know that I can't do it myself. 712 00:49:40,960 --> 00:49:44,440 I have to have that illusion of control shattered. 713 00:49:44,440 --> 00:49:47,840 He has managed to stay clean for three years 714 00:49:47,840 --> 00:49:51,280 and now helps other people working to beat their addictions. 715 00:49:51,280 --> 00:49:54,800 Truth is, I never, ever want to go back to it. Never. 716 00:49:54,800 --> 00:50:02,000 Because no matter how long I chased that first high I never got close to it, never got close to it again. 717 00:50:11,280 --> 00:50:13,280 Quick, cover. Oh, I'm dead. I'm dead. 718 00:50:14,680 --> 00:50:19,800 It's 1:00 am and Liam is at a friend's house for a session on the Xbox. 719 00:50:19,800 --> 00:50:24,440 He's been doing coke for several hours now. 720 00:50:28,680 --> 00:50:32,440 Best one, that was, for me. Been trying to chill out all afternoon. 721 00:50:32,440 --> 00:50:35,080 Had that now, so feel sound, like. 722 00:50:36,800 --> 00:50:38,600 Look at him! Watch this - bang! 723 00:50:38,600 --> 00:50:41,760 And look - get him out the fence, man! 724 00:50:41,760 --> 00:50:48,160 But pretty soon, a day of drinking and doing lines begins to take its toll on Liam. 725 00:50:48,160 --> 00:50:54,800 Can't chill out, man. Really agitated, had a few lines. Just creeps up on you, as well. 726 00:50:54,800 --> 00:50:58,040 I've been drinking most of the day 727 00:51:01,240 --> 00:51:04,280 Cocaine causes the adrenal glands to produce cortisol - 728 00:51:04,280 --> 00:51:06,080 the stress hormone. 729 00:51:07,600 --> 00:51:12,760 This normally happens when we're in threatening situations, to prepare us for physical action. 730 00:51:14,280 --> 00:51:19,560 Elevated levels of the hormone also make people feel anxious and restless. 731 00:51:19,560 --> 00:51:23,800 The longer a cocaine session lasts the more these unpleasant feelings can be felt 732 00:51:23,800 --> 00:51:26,360 as the level of cortisol rises. 733 00:51:26,360 --> 00:51:28,720 Mate, this is dead hard. 734 00:51:28,720 --> 00:51:32,520 Feel really spaced out now, just want to go home and lie on my bed. 735 00:51:32,520 --> 00:51:35,600 Going to be tossing and turning, doing my head in, like. 736 00:51:35,600 --> 00:51:41,800 Meanwhile, over in Bristol, Damian's supplies of cocaine have run out 737 00:51:41,800 --> 00:51:44,600 and the party is starting to wind down. 738 00:51:44,600 --> 00:51:48,240 Evening's been cool, enjoyed myself, 739 00:51:48,240 --> 00:51:51,240 but the coke's worn down now. 740 00:51:51,240 --> 00:51:54,240 Just need some more, ha! 741 00:51:54,240 --> 00:51:56,280 Kind of winding down, yeah, yeah. 742 00:52:09,880 --> 00:52:15,040 By 11:00am the next morning, everyone is suffering the full effects of a big night. 743 00:52:16,560 --> 00:52:20,160 Damian has disappeared altogether and Josie has only just gone to bed, 744 00:52:20,160 --> 00:52:23,320 surrounded by the aftermath of the party. 745 00:52:23,320 --> 00:52:27,760 Have you seen it, the state of the place? 746 00:52:30,520 --> 00:52:32,520 What time is it? 747 00:52:32,520 --> 00:52:35,080 Have you been to bed? 748 00:52:36,600 --> 00:52:41,680 What do you think? It's bed time now. 749 00:52:41,680 --> 00:52:45,440 That's all I've got to say on the matter. 750 00:52:49,320 --> 00:52:54,000 Cocaine can cause people to feel down the next day, just like alcohol. 751 00:52:54,000 --> 00:52:58,440 Liam is hoping that a fry-up might make the world seem a better place. 752 00:52:58,440 --> 00:53:01,160 His friend's identity is concealed for legal reasons. 753 00:53:01,160 --> 00:53:04,360 I'll have a large breakfast. Two breakfasts. 754 00:53:07,160 --> 00:53:11,280 I feel quite intoxicated, I do. You know when you're just like... 755 00:53:11,280 --> 00:53:13,000 Feel like shite. Feel poisoned. 756 00:53:14,840 --> 00:53:17,960 I feel a bit drained, to be fair. 757 00:53:17,960 --> 00:53:21,360 Takes it out of you. Never again. 758 00:53:21,360 --> 00:53:25,680 It makes you feel bad after a blow out, the day after. 759 00:53:25,680 --> 00:53:30,160 When I have been on a session I get a bit cranky, mardy, 760 00:53:30,160 --> 00:53:34,440 I supposed I've had no sleep or been trying to get to sleep. 761 00:53:38,800 --> 00:53:44,800 The cocaine hangover is down to the way in which the drug makes users feel high. 762 00:53:44,800 --> 00:53:47,640 The euphoria of cocaine comes from the release of 763 00:53:47,640 --> 00:53:51,480 large amounts of the feel-good chemical messenger dopamine. 764 00:53:51,480 --> 00:53:57,640 Because the drug blocks the dopamine from being re-cycled, it stays in the gap between nerve cells. 765 00:53:57,640 --> 00:54:00,800 Eventually, it breaks down and disappears. 766 00:54:02,320 --> 00:54:06,680 It takes several days for nerve cells to replenish the stocks of dopamine. 767 00:54:07,680 --> 00:54:12,800 After a cocaine binge, the shortage of dopamine stops the feel-good network functioning properly, 768 00:54:12,800 --> 00:54:15,160 making users feel down. 769 00:54:15,160 --> 00:54:19,880 The cocaine comedown is really about feeling depressed and fed up. 770 00:54:19,880 --> 00:54:23,960 And that is because the brain's dopamine system - 771 00:54:23,960 --> 00:54:28,320 this pleasure chemical - is struggling to get back to normal. 772 00:54:28,320 --> 00:54:33,960 But Liam's hangover is all the worse because the cocaine he took allowed him to drink so much. 773 00:54:33,960 --> 00:54:41,560 It creeps up on you. Don't realise how much you're drinking then it hits you. 774 00:54:41,560 --> 00:54:45,560 But, despite the hangover, it looks like Liam will be heading out again very soon. 775 00:54:46,480 --> 00:54:48,320 Are you getting any more? 776 00:54:48,320 --> 00:54:51,360 I've still got some left. 777 00:54:57,440 --> 00:55:01,480 For Liam, the cocaine hangover is just the price you pay for a big night out 778 00:55:01,480 --> 00:55:04,120 and the drug is part of normal life. 779 00:55:04,120 --> 00:55:10,400 It's everywhere now. I don't know many people that don't have something to do with it. 780 00:55:10,400 --> 00:55:12,120 A lot of people have it. 781 00:55:12,120 --> 00:55:14,560 It's hard to get away from. 782 00:55:14,560 --> 00:55:18,920 But for Tom, using cocaine changed him irreversibly. 783 00:55:18,920 --> 00:55:24,800 Imagine being told that part of your body's not working, and it's your fault because you took cocaine. 784 00:55:28,480 --> 00:55:31,960 Josie and Damian are split on whether they'll give up coke. 785 00:55:31,960 --> 00:55:35,680 I ain't going to give up coke I ain't got no reason to. 786 00:55:35,680 --> 00:55:42,440 I'm going to knock coke on the head quite soon. I'm 29 now, coming into my 30's. 787 00:55:42,440 --> 00:55:48,040 I want to get really on top of my entrepreneurial activities 788 00:55:48,040 --> 00:55:53,120 and I don't think coke has got a part in that at all. 789 00:55:53,120 --> 00:55:57,080 Despite the risks, cocaine maintains its appeal to many. 790 00:55:57,080 --> 00:56:01,440 With its price at an all-time low, it has never been more accessible 791 00:56:01,440 --> 00:56:04,840 and the drug looks set to become a part of more people's lives. 792 00:56:05,680 --> 00:56:12,880 Cocaine has been a remarkably popular drug, globally, for the last 100, 150 years. 793 00:56:12,880 --> 00:56:17,400 I don't think its appeal is going to diminish any time soon. 794 00:56:40,320 --> 00:56:43,360 Subtitles by Red Bee Media Ltd 795 00:56:43,360 --> 00:56:46,400 E-mail subtitling@bbc.co.uk